Withaferin a is a leptin sensitizer with strong antidiabetic properties in mice.

Lee J, Liu J, Feng X, Salazar Hernandez MA, Mucka P, Ibi D, Choi J, Ozcan U. Nature Medicine, 2016 August 1 PubMed: https://www.ncbi.nlm.nih.gov/pubmed/27479085

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